Our goals for this $3M three year project are to collect safety endpoints in patients with obstructive lung diseases, finalize the MagniXene™ dosing and MRI methods, and validate the MagniXene™ results by comparing with the existing clinical methods for assessing lung function and microstructure.

The hyperpolarized gas human lung imaging team at Robarts Research Institute and University of Western Ontario

If New Hampshire’s proposal is selected, UNH and Xemed will collaborate with researchers at the DOE’s Spallation Neutron Source (pictured) and Thomas Jefferson National Accelerator Laboratory on next-generation 3He polarization systems

Kai Ruppert (UVa), Isabel Dregely (UNH), and Bill Hersman (UNH and Xemed) at the ISMRM Young Investigator Award ceremony
MagniXene™ single-breath MR image of a 22 y.o. female healthy volunteer. 0.7L bolus, voxel size =3.1 x 3.1 x 10mm. GRE image acquired using the Siemens Tim Trio at the Center for In-Vivo Hyper-polarized Gas Studies at the University of Virginia.
Image credits: T. A. Altes, G. W. Miller, J. P. Mugler, III, K. Ruppert

Xemed CEO Bill Hersman checks polarizer status
with undergraduate intern Igor Tsentalovich
Two new SBIR Phase 1 grants awarded from the US Department of Energy to Xemed to develop nuclear physics applications for its HeliBox-Z100 helium-3 polarizer

Back row standing: Bill Hersman, Sean Fain, Dave Watt, Tally Altes, Iulian Ruset, Jeff Ketel, Isabel Dregely, Jan Distelbrink
Middle kneeling: Walt Porter, Jeff Ortakales
Front row: Steve Bryn, Steve, Ketel, Christina Johnson, Aaron Hope